Mission statement: In an interdisciplinary environment, combining Analytical Chemistry, Synthetic Chemistry, Biology and Medicine, we are interested in modes of action of approved drugs, drug candidates and investigational drugs to tackle chronic diseases. We use post-genomic methods to uncover molecular mechanisms of drug action from preclinical in vitro models to the analysis of patient samples. Our research focusses on target identification and anticancer strategies beyond cytotoxicity with an additional incentive on drug exposure. We believe that a detailed understanding of targets, off-targets and modes of action of therapeutic compounds will allow their precise application for the improved benefit of patients.

We work in close collaboration with the Gerner-Lab, the Institute of Inorganic Chemistry and the Joint Metabolome Facility.