Publications
2024
Hagn G, Meier-Menches SM, Plessl-Walder G, Mitra G, Mohr T, Preindl K et al. Plasma Instead of Serum Avoids Critical Confounding of Clinical Metabolomics Studies by Platelets. Journal of Proteome Research. 2024 Aug 2;23(8):3064-3075. Epub 2024 Mar. doi: 10.1021/acs.jproteome.3c00761
Skos L, Schmidt C, Thomas SR, Park M, Geiger V, Wenisch D et al. Gold-templated covalent targeting of the CysSec-dyad of thioredoxin reductase 1 in cancer cells. Cell Reports Physical Science. 2024 Jul 17;5(7):102072. doi: 10.1016/j.xcrp.2024.102072
Janker-Bortel P, Hagn G, Skos L, Bileck A, Paulitschke V, Paulitschke P et al. Memory effects of prior subculture may impact the quality of multiomic perturbation profiles. Proceedings of the National Academy of Sciences of the United States of America. 2024 Jul 16;121(29):e2313851121. doi: 10.1073/pnas.2313851121
Pai V, Bileck A, Hommer N, Janku P, Lindner T, Kauer V et al. Impaired retinal oxygen metabolism and perfusion are accompanied by plasma protein and lipid alterations in recovered COVID-19 patients. Scientific Reports. 2024 Apr 10;14(1):8395. doi: 10.1038/s41598-024-56834-4
Long D, Eade L, Sullivan MP, Dost K, Meier-Menches SM, Goldstone DC et al. AdductHunter: identifying protein-metal complex adducts in mass spectra. Journal of Cheminformatics. 2024 Feb 6;16(1):15. doi: 10.1186/s13321-023-00797-7
Borutzki Y, Meier-Menches SM, McNamara LE, Anderson JS. Investigating biological effects of a novel organometallic complex as potential theranostic agent. Naunyn-Schmiedeberg's Archives of Pharmacology. 2024;397(Suppl.1):S36-S36. P078.
2023
Fetahu IS, Esser-Skala W, Dnyansagar R, Sindelar S, Rifatbegovic F, Bileck A et al. Single-cell transcriptomics and epigenomics unravel the role of monocytes in neuroblastoma bone marrow metastasis. Nature Communications. 2023 Dec;14(1):3620. doi: 10.1038/s41467-023-39210-0
Baier D, Mendrina T, Schoenhacker-Alte B, Pirker C, Mohr T, Rusz M et al. The Lipid Metabolism as Target and Modulator of BOLD-100 Anticancer Activity: Crosstalk with Histone Acetylation. Advanced science. 2023 Nov 14;10(32):2301939. doi: 10.1002/advs.202301939
Borutzki Y, Skos L, Gerner C, Meier-Menches SM. Exploring the Potential of Metal-Based Candidate Drugs as Modulators of the Cytoskeleton. ChemBioChem. 2023 Sep 1;24(17):e202300178. doi: 10.1002/cbic.202300178
Janker L, Schuster D, Bortel P, Hagn G, Meier-Menches SM, Mohr T et al. Multi-omics empowered deep phenotyping of ulcerative colitis identifies biomarker signatures reporting functional remission states. Journal of Crohn's & colitis. 2023 Sep 1;17(9):1514-1527. doi: 10.1093/ecco-jcc/jjad052
Zappe K, Kopic A, Scheichel A, Schier AK, Schmidt LE, Borutzki Y et al. Aberrant DNA Methylation, Expression, and Occurrence of Transcript Variants of the ABC Transporter ABCA7 in Breast Cancer. Cells. 2023 Jun;12(11):1462. doi: 10.3390/cells12111462
Skos L, Borutzki Y, Gerner C, Meier-Menches SM. Methods to identify protein targets of metal-based drugs. Current opinion in chemical biology. 2023 Apr;73:102257. doi: 10.1016/j.cbpa.2022.102257
Hofbauer TM, Distelmaier K, Muqaku B, Spinka G, Seidl V, Arfsten HT et al. Metabolomics implicate eicosanoids in severe functional mitral regurgitation. ESC Heart Failure. 2023 Feb;10(1):311-321. Epub 2022 Oct 10. doi: 10.1002/ehf2.14160
Kovarik JJ, Bileck A, Hagn G, Meier-Menches SM, Frey T, Kaempf A et al. A multi-omics based anti-inflammatory immune signature characterizes long COVID-19 syndrome. Iscience. 2023 Jan 20;26(1):105717. doi: 10.1016/j.isci.2022.105717
Fuchs V, Cseh K, Hejl M, Vician P, Neuditschko B, Meier-Menches SM et al. Highly Cytotoxic Molybdenocenes with Strong Metabolic Effects Inhibit Tumour Growth in Mice. Chemistry: A European Journal. 2023 Jan 18;29(4):e202202648. doi: 10.1002/chem.202202648
2022
Neuditschko B, King AP, Huang Z, Janker L, Bileck A, Borutzki Y et al. An Anticancer Rhenium Tricarbonyl Targets Fe-S Cluster Biogenesis in Ovarian Cancer Cells. Angewandte Chemie (International Edition). 2022 Oct 24;61(43):e202209136. doi: 10.1002/anie.202209136
Brunmair J, Bileck A, Schmidl D, Hagn G, Meier-Menches SM, Hommer N et al. Metabolic phenotyping of tear fluid as a prognostic tool for personalised medicine exemplified by T2DM patients. The EPMA journal. 2022 Mar;13(1):107-123. doi: 10.1007/s13167-022-00272-7
Prechova M, Adamova Z, Schweizer AL, Maninova M, Bauer A, Kah D et al. Plectin-mediated cytoskeletal crosstalk controls cell tension and cohesion in epithelial sheets. Journal of Cell Biology. 2022 Feb 9;221(3):e202105146. doi: 10.1083/jcb.202105146
Meier-Menches SM, Neuditschko B, Janker L, Gerner MC, Schmetterer KG, Reichle A et al. A Proteomic Platform Enables to Test for AML Normalization In Vitro. Frontiers in Chemistry. 2022 Feb 1;10:826346. doi: 10.3389/fchem.2022.826346
Baier D, Schönhacker-Alte B, Rusz M, Pirker C, Mohr T, Mendrina T et al. The Anticancer Ruthenium Compound BOLD-100 Targets Glycolysis and Generates a Metabolic Vulnerability towards Glucose Deprivation. Pharmaceutics. 2022 Jan 20;14(2):238. doi: 10.3390/pharmaceutics14020238